Figure 4 | Scientific Reports

Figure 4

From: Warfarin and coumarin-like Murraya paniculata extract down-regulate EpCAM-mediated cell adhesion: individual components versus mixture for studying botanical metastatic chemopreventives

Figure 4

Concentration-dependent inhibition by warfarin, Z3, Z5 and CM on adhesion of HCT116 to HUVECs.

(a) warfarin, CM, Z3 and Z5 interfered with adhesion of Rhodamine 123-labeled HCT116 cells to HUVEC monolayer stimulated by IL-1β (1 ng/mL). (b) quantitative analysis of the concentration-dependent effect of warfarin, CM, Z3 and Z5 and warfarin on adhesion of HCT116 cells to HUVECs. Bars represent the mean ± SEM (n = 3). *P < 0.05 and **P < 0.01, compared with the control.

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