Table 3 Relationship between serum thyroid profiles and di-(2-ethylhexyl) phthalate (DEHP) intake estimated by questionnaire and DEHP estimates by creatinine excretion-based model in multivariate linear regression models after multiple imputation.

From: Intake of Phthalate-tainted Foods and Serum Thyroid Hormones in Taiwanese Children and Adolescents

 

Crude

Adjusted Model 1

N

β

SE

P

P*

β

SE

P

P*

T3

 Daily DEHP intake (DDI) estimated by questionnaire

250

0.07

0.03

0.01

0.04

0.04

0.03

0.11

0.23

 DEHP intake estimated by creatinine excretion-based model 2

240

0.15

0.32

0.64

0.64

0.05

0.29

0.86

0.86

T4

 Daily DEHP intake (DDI) estimated by questionnaire

250

0.001

0.002

0.65

0.76

−0.002

0.002

0.38

0.51

 DEHP intake estimated by creatinine excretion-based model 2

240

−0.01

0.02

0.64

0.64

−0.02

0.02

0.27

0.54

FT4

 Daily DEHP intake (DDI) estimated by questionnaire

250

0.00005

0

0.76

0.76

0.00006

0

0.72

0.72

 DEHP intake estimated by creatinine excretion-based model 2

240

0.002

0.002

0.39

0.64

0.001

0.002

0.46

0.61

TSH

 Daily DEHP intake (DDI) estimated by questionnaire

250

0.003

0.001

0.04

0.07

0.002

0.001

0.09

0.23

 DEHP intake estimated by creatinine excretion-based model 2

240

0.04

0.02

0.01

0.04

0.04

0.02

0.02

0.08

  1. Abbreviations: BMI = body mass index; DDI = daily DEHP intake; DEHP = di-(2-ethylhexyl) phthalate; FT4 = free thyroxine; T3 = triiodothyronine; T4 = thyroxine; TSH = thyroid-stimulating hormone.
  2. *Benjamini-Hochberg adjusted P values.
  3. 1Adjusting for age, gender, BMI.
  4. 2Ten missing data.