Figure 7: Prevalence of neuronal phenotypes within human SNC subdivisions.
From: Glutamate neurons are intermixed with midbrain dopamine neurons in nonhuman primates and humans
(A) Coronal section showing TH-expression in the human SNC. (B) Distribution of VGluT2-only neurons (green circles), TH-only neurons (blue triangles) and dual VGluT2-TH neurons (red circles) within the different subdivisions of the human SNC. The SNC has mostly TH-only neurons within all subdivisions and infrequent VGluT2 neurons that are confined to the SNCl. Data are mean ± SEM percent neuronal phenotype within each subdivision per analyzed section. (C) Detection of a TH-only neuron (blue arrow) and a VGluT2-only neuron (green) within the SNCl. Scale bar in A = 250 μm, scale bar in C = 250 μm and applies to C-C”.
