Table 1 Marmoset VTA neurons expressing VGluT2 mRNA or TH-immunoreactivity.

From: Glutamate neurons are intermixed with midbrain dopamine neurons in nonhuman primates and humans

VTA Subdivision

Subject

VGluT2-only

VGluT2-TH

TH-only

VTAR

Turk

93.98% (n = 234)

3.61% (n = 9)

2.41% (n = 6)

Dew

83.67% (n = 456)

7.16% (n = 39)

9.17% (n = 50)

Wen

73.06% (n = 198)

7.38% (n = 20)

19.56% (n = 53)

Mean ± SEM

83.57% ± 6.04%

6.05% ± 1.22%

10.38% ± 4.99%

RLi

Turk

58.95% (n = 313)

3.01% (n = 16)

38.04% (n = 202)

Dew

41.06% (n = 216)

3.04% (n = 16)

55.89% (n = 294)

Wen

56.2% (n = 272)

2.89% (n = 14)

40.91% (n = 198)

Mean ± SEM

52.07% ± 5.56%

2.98% ± 0.05%

44.95% ± 5.54%

CLi

Turk

25.42% (n = 30)

1.69% (n = 2)

72.88% (n = 86)

Dew

25.76% (n = 17)

1.52% (n = 1)

72.73% (n = 48)

Wen

13.73% (n = 7)

1.96% (n = 1)

84.31% (n = 43)

Mean ± SEM

21.64% ± 3.96%

1.72% ± 0.13%

76.64% ± 3.84%

VTAC

Turk

41.27% (n = 26)

1.59% (n = 1)

57.14% (n = 36)

Dew

34.38% (n = 11)

9.38% (n = 3)

56.25% (n = 18)

Wen

40.82% (n = 20)

4.08% (n = 2)

55.1% (n = 27)

Mean ± SEM

38.82% ± 2.23%

5.01% ± 2.3%

56.16% ± 0.59%

IF

Turk

16.48% (n = 15)

1.1% (n = 1)

82.42% (n = 75)

Dew

25% (n = 30)

5% (n = 6)

70% (n = 84)

Wen

30.7% (n = 35)

0% (n = 0)

69.3% (n = 79)

Mean ± SEM

24.06% ± 4.13%

2.03% ± 1.52%

73.91% ± 4.26%

PN

Turk

21.43% (n = 24)

0.89% (n = 1)

77.68% (n = 87)

Dew

18.32% (n = 37)

3.96% (n = 8)

77.72% (n = 157)

Wen

42.47% (n = 31)

1.37% (n = 1)

56.16% (n = 41)

Mean ± SEM

27.4% ± 7.58%

2.07% ± 0.95%

70.52% ± 7.18%

PIF

Turk

19.44% (n = 7)

2.78% (n = 1)

77.78% (n = 28)

Dew

20% (n = 29)

7.59% (n = 11)

72.41% (n = 105)

Wen

19.05% (n = 4)

0% (n = 0)

80.95% (n = 17)

Mean ± SEM

19.5% ± 0.28%

3.45% ± 2.22%

77.05% ± 2.49%

PBP

Turk

30.89% (n = 303)

11.42% (n = 112)

57.7% (n = 566)

Dew

17.44% (n = 198)

23.17% (n = 263)

59.38% (n = 674)

Wen

20.48% (n = 144)

19.49% (n = 137)

60.03% (n = 422)

Mean ± SEM

22.94% ± 4.07%

18.03% ± 3.47%

59.04% ± 0.7%

  1. Percent refers to the number of neurons expressing VGluT2 mRNA without TH-immunoreactivity (VGluT2-only neurons), neurons co-expressing VGluT2 mRNA and TH-immunoreactivity (VGluT2-TH neurons), or neurons expressing TH-immunoreactivity without VGluT2 mRNA (TH-only neurons) divided by the total number of labeled neurons identified in each subject and in each subdivision of the VTA. Numbers in parentheses refer to number of counted neurons of each phenotype.
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