Table 4 Human SNC neurons expressing VGluT2 mRNA or TH-immunoreactivity.
From: Glutamate neurons are intermixed with midbrain dopamine neurons in nonhuman primates and humans
SNC Subdivision | Subject | VGluT2-only | VGluT2-TH | TH-only |
|---|---|---|---|---|
SNCd | Subject 1 | 1.8% (n = 4) | 2.7% (n = 6) | 95.5% (n = 212) |
Subject 2 | 3.45% (n = 33) | 2.61% (n = 25) | 93.94% (n = 899) | |
Mean ± SEM | 2.63% ± 0.82% | 2.66% ± 0.05% | 94.72% ± 0.78% | |
SNCv | Subject 1 | 0% (n = 0) | 0% (n = 0) | 100% (n = 40) |
Subject 2 | 1.07% (n = 18) | 3.2% (n = 54) | 95.74% (n = 1617) | |
Mean ± SEM | 0.53% ± 0.53% | 1.6% ± 1.6% | 97.87% ± 2.13% | |
SNCm | Subject 1 | 1.78% (n = 6) | 0.3% (n = 1) | 97.92% (n = 330) |
Subject 2 | 1.19% (n = 9) | 0.4% (n = 3) | 98.42% (n = 747) | |
Mean ± SEM | 1.48% ± 0.3% | 0.35% ± 0.05% | 98.17% ± 0.25% | |
SNCl | Subject 1 | 19.05% (n = 12) | 4.76% (n = 3) | 76.19% (n = 48) |
Subject 2 | 7.73% (n = 28) | 1.1% (n = 4) | 91.16% (n = 330) | |
Mean ± SEM | 13.39% ± 5.66% | 2.93% ± 1.83% | 83.68% ± 7.48% |
