Figure 3 | Scientific Reports

Figure 3

From: Gold Nanoparticle–Mediated Targeted Delivery of Recombinant Human Endostatin Normalizes Tumour Vasculature and Improves Cancer Therapy

Figure 3

In vivo distribution of rhES in different organs at 30 min and 4 h.

(a) rhES accumulation in tumours was much greater following treatment with rhES-AuNPs-PEG than with rhES (*P < 0.05) within 30 min after intravenous injection. (b) After 4 h, the rhES levels in tumours treated with rhES-AuNPs-PEG were maintained at high levels; however, the accumulation of rhES in tumours treated with rhES monotherapy still much lower than those treated with rhES-AuNPs-PEG (*P < 0.05).

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