Figure 6

HPLC analysis of 5-FU in different organs.
After intraperitoneal 5-FU injection, the concentration of 5-FU in tumours increased significantly in mice pre-treated with rhES-AuNPs-PEG compared with treatment with 5-FU alone (a) (*P < 0.05). rhES-AuNPs-PEG treatment did not increase 5-FU concentrations in the kidneys (b) or livers (c) compared with 5-FU alone.