Table 1 Comparison of phylotype coverage and diversity estimation of the 16S rRNA gene libraries at 97% similarity from the pyrosequencing analysis.

From: Alterations in the Fecal Microbiota of Patients with HIV-1 Infection: An Observational Study in A Chinese Population

Group

No. of reads

No. of OTUs 1

Good’s(%) 2

Richness estimator

Diversity index

ACE

95%CI

Chao 1

95%CI

Shannon

Simpson

Control

119360

2943

98.41%

14008

13387.1–14665.5

7875

7235.1–8610.8

3.916467

0.063107

Treated

287415

4817

98.96%

19732

19057.0–20440.0

11270

10622.5–11990.7

4.303014

0.037468

Untreated

247471

5276

98.69%

20126

19466.3–20816.1

12136

11473.3–12869.8

4.328113

0.042655

  1. 1The operational taxonomic units (OTUs) were defined at a 97% similarity level.
  2. 2The coverage percentage (Good’s) and richness estimators (ACE and Chao1) and diversity indices (Shannon and Simpson) were calculated using Good’s method and the mothur program, respectively.
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