Table 4 Patient-specific skin biopsies obtained and cultured under cGMP conditions using in house developed xeno-free fibroblast culture media (IxMedia).

From: cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness

Biopsy #	Age	OD VA	OS VA	Clinical Diagnosis	Gender	Molecular Diagnosis
DB-001	72	20/100	20/100	Retinitis Pigmentosa	Male	MAK
DB-002	86	20/40	20/100	Age Related Macular Degeneration	Male	CFH, ARMS2
DB-003	28	HM	LP	Leber Congenital Amaurosis	Male	None
DB-004	79	20/100	20/80	Retinitis Pigmentosa	Male	USH2A
DB-005	47	NLP	NLP	Retinitis Pigmentosa	Female	BBS1
DB-006	32	NLP	NLP	Retinitis Pigmentosa	Male	PCDH21
DB-007	81	NLP	LP	Retinitis Pigmentosa	Male	MAK
DB-008	54	NLP	LP	Leber Congenital Amaurosis	Male	RDH12
DB-009	57	20/1000	LP	Retinitis Pigmentosa	Female	RHO
DB-010	69	LP	LP	Retinitis Pigmentosa	Male	BBS1
DB-011	67	NLP	LP	Retinitis Pigmentosa	Female	PCDH21
DB-012	54	NLP	NLP	Retinitis Pigmentosa	Female	None
DB-013	58	HM	NLP	Leber Congenital Amaurosis	Male	RPGRIP1
DB-014	41	LP	5/350	Retinitis Pigmentosa	Female	CERKL
Db-015	61	20/150	NLP	Usher Syndrome	Male	USH2A
DB-016	65	1/350	LP	Retinitis Pigmentosa	Female	None
DB-017	17	LP	LP	Leber Congenital Amaurosis	Female	None
DB-018	67	LP	LP	X-linked Retinitis Pigmentosa	Male	RPGR
DB-019	41	LP	LP	Usher Syndrome	Male	SLC26A4
DB-020	69	20/60	LP	Choroideremia	Male	CHM
DB-021	67	20/100	LP	Retinitis Pigmentosa	Male	PRPF8
DB-022	57	LP	CF	Leber Congenital Amaurosis	Male	NMNAT1
DB-023	58	LP	LP	Retinitis Pigmentosa	Male	BBS1
DB-024	23	LP	LP	Batten Disease	Female	CLN3
DB-025	37	HM	LP	Leber Congenital Amaurosis	Male	CEP290
DB-026	61	HM	LP	Retinitis Pigmentosa	Male	None
DB-027	58	HM	LP	Retinitis Pigmentosa	Male	USH2A
DB-028	63	LP	LP	Usher Syndrome	Female	USH2A
DB-029	65	HM	20/80	Usher Syndrome	Male	USH1C
DB-030	73	HM	LP	Choroideremia	Male	CHM
DB-031	49	CF	20/50	Usher Syndrome	Male	USH2A
DB-032	45	20/50	20/50	Usher Syndrome	Male	PCDH15
DB-033	47	20/40	20/40	Usher Syndrome	Female	PCDH15
DB-034	71	NLP	NLP	Retinitis Pigmentosa	Male	RPGR
DB-035	61	LP	LP	Retinitis Pigmentosa	Male	RPGR

Age = patient age at biopsy, OD VA = Visual acuity of the right eye, OS VA = Visual acuity of the left eye. HM = hand motion, CF = counts fingers, LP = light perception, NLP = no light perception.

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Table 4 Patient-specific skin biopsies obtained and cultured under cGMP conditions using in house developed xeno-free fibroblast culture media (IxMedia).

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