Figure 4 | Scientific Reports

Figure 4

From: Msh2 deficiency leads to dysmyelination of the corpus callosum, impaired locomotion and altered sensory function in mice

Figure 4

MBP expression and in vivo MRI.

(a) Quantification by densitometry of all the isoforms of MBP protein levels in the corpus callosum normalized to GAPDH signal shows low expression of myelin basic protein (MBP) in the Msh2−/− mice compared to that in WT mice. Error bars represent SD (n = 3 for each genotype). (b) Corpus callosum volumes determined by MRI and normalized to brain volume were significantly smaller in the Msh2−/−. Error bars represent SD (n = 4 for each genotype).

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