Figure 6

Impaired locomotion and sensation in Msh2−/− mice.
(a) Mice were placed in an open-field chamber equipped with infrared sensors. Total distance traveled (in centimeters) was measured for each group of five mice. Msh2−/− mice walked a significantly shorter distance than did the WT mice. Error bars represent SD (n = 5 for each genotype). (b) Mice were placed in an open-field chamber equipped with infrared sensors. Anxiety index is the ratio between the time in the center and the time in the periphery (n = 5 for each genotype).