Figure 4 | Scientific Reports

Figure 4

From: Theophylline controllable RNAi-based genetic switches regulate expression of lncRNA TINCR and malignant phenotypes in bladder cancer cells

Figure 4

Validation of theo-RNAi switches of BCa cells.

(A) TINCR expression level following the treatment of BCa cells with amiRNAs. The amiRNA-TINCR could significantly knock-down TINCR in both 5637 and SW780. Bars: mean ± SD; **P < 0.01. (D,E) TINCR expression level following the treatment of BCa cells with the OFF device at varying concentration of theophylline. Bars: mean ± SD; P < 0.01. (F,G) And the ON device. Bars: mean ± SD; P < 0.01. (B,C) TINCR expression level following the treatment of BCa cells with the mutant theo-RNAi switches at 0/2 mM theophylline. Bars: mean ± SD; **P < 0.01.

Back to article page