Figure 8: Inhibiting postsynaptic PKA activity did not prevent the ethanol-induced inhibition of the facial stimulation-evoked outward currents. | Scientific Reports

Figure 8: Inhibiting postsynaptic PKA activity did not prevent the ethanol-induced inhibition of the facial stimulation-evoked outward currents.

From: Ethanol modulates facial stimulation-evoked outward currents in cerebellar Purkinje cells in vivo in mice

Figure 8

(A) With 5 μM PKI in the pipette internal solution, representative membrane currents traces evoked by facial stimulation (30 ms, 60 psi) in a PC in treatments of ACSF, ethanol (300 mM) and washout. (B,C) Bar graphs show the normalized amplitude (B) and AUC (C) of the outward currents in treatments of ACSF, ethanol and washout. (D,E) Bar graphs show that the normalized amplitude (D) and AUC (E) of the facial stimulation-evoked outward currents using normal pipette internal solution (PKI out) and PKI included pipette internal solution (PKI in). n = 6 cells per group. *P < 0.05 vs ACSF.

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