Table 2 Estimated rates of nucleotide substitution and TMRCA of H5N2 outbreaks in British Columbia and Ontario Canada, 2014 and 2015.

From: Epidemiological and Evolutionary Inference of the Transmission Network of the 2014 Highly Pathogenic Avian Influenza H5N2 Outbreak in British Columbia, Canada

Gene

Substitution rate (x 10−3)

TMRCAb (day/month/year)

Mean

95% HPDa

Mean

95% HPD

HA

12.14

5.34–20.00

12/06/2014

26/05/2014–07/07/2014

NS

11.39

2.93–22.10

23/07/2014

29/05/2014–23/10/2014

NA

9.1

2.41–16.80

22/08/2014

08/06/2014–15/12/2014

PB1

7.44

2.22–13.60

08/07/2014

28/05/2014–09/09/2014

PA

6.91

2.17–12.00

05/07/2014

30/05/2014–31/08/2014

NP

5.53

0.99–10.70

31/07/2014

28/05/2014–27/11/2014

M

4.92

0.64–10.50

27/07/2014

26/05/2014–04/12/2014

PB2

4.51

1.30–8.17

16/07/2014

30/05/2014–27/09/2014

  1. a95% highest posterior density intervals.
  2. btime of most recent common ancestor.
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