Figure 4: Engraftment of administered MSCs. | Scientific Reports

Figure 4: Engraftment of administered MSCs.

From: Mesenchymal stem cells protect against the tissue fibrosis of ketamine-induced cystitis in rat bladder

Figure 4

(a) Fluorescent immunohistochemical detection of GFP-expressing MSCs in the bladder 7 day after the administration of MSCs stably expressing GFP. The region characterized by GFP+ cells (box in upper image; magnification ×100, scale bar = 200 μm) is shown in the lower panel at higher magnification (×200, scale bar = 50 μm). Nuclei were stained with DAPI (blue). * Indicates the auto-fluorescence signal from DAPI- red blood cells. (b) Colocalization of GFP+ cells with vimentin+ stromal (left panel) and β-catenin+ urothelium (right panel) tissue in the KC bladder tissues. The upper and lower panel images are magnified ×100 (scale bar = 100 μm) and ×400 (scale bar = 20 μm), respectively. Arrow indicates the differentiated cells.

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