Figure 5 | Scientific Reports

Figure 5

From: Screening differential circular RNA expression profiles reveals the regulatory role of circTCF25-miR-103a-3p/miR-107-CDK6 pathway in bladder carcinoma

Figure 5

Prediction for circRNA/miRNA interactions and miRNA-mediated signaling pathways.

(A) The interaction of circTCF25-miR-103a-3p/miR-107 was predicted based on TargetScan and miRanda. (B) The heatmap reveals statistically significant correlations between miR-103a-3p or miR-107 and their mediated pathways by P-value (log scaled). Red represents high significance. (C) The Venn diagram indicates the relevant pathways of miR-107 mediated, miR-103a-3p mediated and miR-103a-3p and miR-107 jointly mediated. Pathways in cancer and PI3K-Akt signaling pathway are intersected. (D) The bar graph indicates the magnitudes of the significant correlation about Pathways in cancer or PI3K-Akt signaling among miR-107 mediated, miR-103a-3p mediated and miR-103a-3p and miR-107 jointly mediated by P-value (−log2 scaled). (E,F) The bar graphs show the magnitudes of the significant correlations about miR-103a-3p and miR-107 mediated signaling pathways respectively by P-value (−log2 scaled).

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