Table 4 The information of network generated by IPA analysis.

From: Genome-wide association study of aggressive behaviour in chicken

The 10th Top Diseases and Functions

Gene Symbol (n = 17)

Focus Molecule

Developmental disorder; Endocrine system disorders; Hereditary disorder; Organismal injury and abnormalities; Reproductive system disease; Skeletal and muscular disorders; Cellular compromise; Cellular function and maintenance; Protein degradation; Protein synthesis.

TET2, TET31, CHST112, L-dopa, GPC33, CTNNBIP12, dopamine, GPC43, SORCS21,2, PPP2R5E, CRY12, BDNF, NGF, NGFR, HTT1,2, ARHGAP262,4, KLF5

17 (9 Molecules associated with aggressive-behaviour from GWAS-SNPs results)

  1. The Gene Symbol in “Bold” indicates that the gene was significantly associated with aggression behaviour traits. “1” indicates that the gene was associated with T1 aggressive-behaviour phenotype; “2” indicates that the gene was associated with T2 aggressive-behaviour phenotype; “3” indicates that the gene was associated with T3 aggressive-behaviour phenotype; “4” indicates that the gene was associated with T4 aggressive-behaviour phenotype.
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