Table 2 Topology parameters of wild type and mutant networks.

System	Clustering coefficient	Network density	Network centralization	Network heterogeneity	Avg. number of neighbors
Apo riboswitch	0.405	0.060	0.045	0.325	3.458
Bound riboswitch	0.479	0.069	0.068	0.358	4.10
M1	0.477	0.064	0.076	0.334	3.729
M2	0.478	0.072	0.066	0.312	4.233
M3	0.422	0.067	0.053	0.325	3.967
M4	0.468	0.063	0.022	0.244	3.733
M5	0.437	0.059	0.044	0.347	3.467
M6	0.441	0.066	0.039	0.312	3.831
MS1	0.449	0.065	0.044	0.382	3.649
MS2	0.449	0.069	0.086	0.369	4.10

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