Figure 1 | Scientific Reports

Figure 1

From: The CD4+ T cell methylome contributes to a distinct CD4+ T cell transcriptional signature in Mycobacterium bovis-infected cattle

Figure 1

Gene expression profiles of CD4+ T lymphocytes from healthy controls and M. bovis infected cattle.

The similarity in expression profiles between all animals (n = 10) was visualised using an MDS plot, produced with EdgeR (A). The read counts for individual genes were compared between all biological replicates. Control animals (C1–C5) were clustered seperately from infected animals (I1-15) on the basis of transcriptomic profiles. 95 genes that were significantly differentially expressed with an FDR <0.05 and log2FC +/−2 are shown (B). Upregulated gene expression is shown in red whereas downregulated expression is shown in green. The colour change represents z-scores that are calculated for each gene. Z-scores scales each gene to have a mean = 0 and standard deviation = 1.

Back to article page