Figure 3
From: A VEGF-dependent gene signature enriched in mesenchymal ovarian cancer predicts patient prognosis
The VDGs predicts patient prognosis in HGS-OvCa.
(A) Upregulation of the VDGs in microdissected tumor stroma versus epithelial tissues (5 samples). (B) Downregulation of the VDGs in PDX versus matched primary tumors (9 samples). (C) Kaplan Meier curves for the two prognostic groups of TCGA samples classified by the VDGs. (D) Kaplan Meier curves for meta-analysis of 681 HGS-OvCa expression profiles across four cohorts. (E) Higher VDGs scores in HGS-OvCa patients with residual disease after debulking surgery.
