Figure 1
From: p18 inhibits reprogramming through inactivation of Cdk4/6

p18 expression is inversely correlated with pluripotency.
(A) Relative expression of p18 mRNA in MEF, ESC and iPSC. The results are presented as the mean ± SD of three independent experiments; ***P < 0.001. (B) Expression of p18 protein in MEF, iPSC and ESC. Actin serves as a loading control. (C) Relative expression of p18 mRNA in MEF, reprogramming cells at day 6 and estabolished iPSC. The results are presented as the mean ± SD of three independent experiments; **P < 0.01; ***P < 0.001.