Figure 6
From: Control of cortex development by ULK4, a rare risk gene for mental disorders including schizophrenia
Ulk4 knockdown leads to decreased acetylation of α-tubulin both in vitro and in vivo.
(A,B) Primary cultured neurons transfected with shRNA268 display less α-acetylated tubulin (n = 3). Two-tailed student’s t tests. *p < 0.05. (C–H) Compared with neurons transfected with control shRNA (C,E,G), cortical neurons incorporated with shRNA268 (D,F,H) displayed reduced expression of α-acetylated tubulin (in red) in vivo. Bars = 25 μm in (C–H).
