Figure 2

Reduced atherosclerotic lesions in 18-weeks old ApoE−/−Adamts4−/− mice.
(a) Photos of the aortic arch. Dotted circle indicates the aortic arch region with prominent lesion. (b) en face ORO stained main trunk of the aortic tree of 18-week old mice. (c) Quantification of the ORO positive area of the en face images shown in panel b (n = 8 for all ApoE−/− and ApoE−/−Adams4−/− mice, n = 4 for C57BL/6J male control mice).