Figure 3
From: Neuoroprotective efficacies by KUS121, a VCP modulator, on animal models of retinal degeneration
Effects of KUS121 on visual function at a later disease stage.
Visual function in 19-month-old rd12 mice administered KUS121 for 6 months up until the examination, or water as a control, was measured by ERG (24 eyes of 15 mice and 26 eyes of 15 mice, respectively). (a) b-wave amplitudes of light adapted ERG at stimulus intensity of 10 or 30 cds/m2. The black bars indicate the average amplitudes. *P < 0.05 (Unpaired t test). (b) Light-adapted ERGs at a stimulus intensity of 30 cds/m2 from 19-month-old rd12 mice that exhibited the median b-wave amplitudes for the control and KUS121 groups, respectively.
