Figure 4 | Scientific Reports

Figure 4

From: Rescuing neuronal cell death by RAIDD- and PIDD- derived peptides and its implications for therapeutic intervention in neurodegenerative diseases

Figure 4

Inhibition capacity of wild type peptides is stronger than that of mutant peptides.

Purified RAIDD DD and PIDD DD were mixed and incubated with the indicated peptides, after which the mixtures were subjected to native-PAGE. Complex formation and inhibition by peptides were then evaluated based on the appearance and disappearance of a new complex band on native-PAGE. The concentration of peptide stock solution was 500 μM. Stock was diluted as indicated and used for complex blocking studies. (B) Bar graph presentation for better visualization of the results of (A). The percentage of the complex was evaluated based on the appearance and thickness of the band generated. The thickness of the complex band formed in the control without any peptide was considered to be 100%. Values are means SD of n = 3.

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