Figure 4 | Scientific Reports

Figure 4

From: HIV-1 Tat exacerbates lipopolysaccharide-induced cytokine release via TLR4 signaling in the enteric nervous system

Figure 4

Cytokine expression and release in Tat mice following LPS treatment in vivo.

Normalized fold mRNA expression of Il-1β (A) and TNF-α (B) of ileum of Tat transgenic mice administered with LPS at a dose of 50 μg/mL in drinking water for 1 week. Tat+ mice were more sensitive to LPS induced increase in cytokine expression. (C) IL-1β protein measured by ELISA. n = 5–6. P < 0.05 (Student’s t test) *Vs Tat− or Tat+.

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