Figure 7 | Scientific Reports

Figure 7

From: HIV-1 Tat exacerbates lipopolysaccharide-induced cytokine release via TLR4 signaling in the enteric nervous system

Figure 7

Tat+ mice were more sensitive to LPS mediated decrease in colonic motility than Tat− mice.

(A) Representative spatiotemporal maps of the mouse ileum with the proximal portion zoomed-in in Tat−. (B) Representative spatiotemporal maps of the mouse ileum with the proximal portion zoomed-in, in Tat+ mice. LPS was administered at a dose of 50 μg/mL, in drinking water for 1 week. (C) Quantification of colonic transit measured as rate of expulsion of natural pellets in 30 min. n = 5–6. P < 0.05 (Students t test) *Vs Tat− or Tat+.

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