Table 4 Meta-regression of peripheral BDNF levels in persons with ASD and healthy controls.

From: Peripheral brain-derived neurotrophic factor in autism spectrum disorder: a systematic review and meta-analysis

Moderator

No. of comparisions

No. of subjects

Meta-regression

Proportion of variance explained

ASD

Controls

Slope

95% CI

P-value

R2 analog

Age (mean, years)

12

1046

1329

−0.1028

−0.285

0.079

0.237

4.66

Gender (% male)

8

710

1075

0.0628

0.0117

0.114

0.024

58.18

Study design

14

1131

1576

0.248

−1.9765

2.4726

0.812

0

Confounders adjustment

14

1131

1576

−1.8329

−3.992

0.326

0.089

19.18

  1. ASD: autism spectrum disorder; No.: number; CI: confidence interval.