Figure 5
Effect of EP peptides on EC proliferation and survival.
(A) Subconfluent HUVEC cultures were incubated in starvation medium with the indicated concentrations of EP3, EP5 and EP6 for 72 h and then counted. VEGF was used as a positive control. P < 0.05 and **P < 0.01 vs basal control. (B) PAEC-VEGFR2 were stimulated with EP6 (50 ng/mL), AcHx (22 ng/mL), AcHn (26 ng/mL) and their combination, or VEGF (50 ng/mL) for 48 h. Cell survival was measured by MTT assay and data are reported as absorbance units (n = 3).
