Table 1 Characteristics of the studies included in meta-analysis of association between hypertension status and prostate cancer risk.

From: Hypertension and risk of prostate cancer: a systematic review and meta-analysis

Study

Year

Region

Study design

No. of cases

Age (yr)

Exposure assessment

Outcome assessment

Matched or adjusted factors

NOS score

Su et al.

2015

Taiwan

Nested case-control

74

54.87 (SD 18.69)

Database

Database

Age, sex, residence and insurance premium

7

Bhindi et al.

2015

Canada

Cohort

2,235

64.9

Measurement

Biopsy

Age, ethnicity, family history of prostate cancer, prostate volume, history of any prior biopsy and 5a-reductase inhibitor use

8

Pai et al.

2015

Taiwan

Cohort

1,971

69.31 (SD 9.31)

Database

Database

Age, income, urbanization level and index day

7

Romero et al.

2012

Brazil

Cohort

58

≥40

Measurement

Biopsy

Age

5

Ganesh et al.

2011

India

Case-control

123

64

Questionnaire

Histologically proven

Age, religion and education

4

Pelucchi et al.

2011

Italy

Case-control

1,294

66 (46–74)

Self-reported

Histologically confirmed

Age, study center, education, smoking, alcohol, physical activity, family history of prostate cancer and nonalcoholic energy intake

7

Wallner et al.

2011

US

Cohort

206

40–79

Physician-diagnosed

Biopsy

Age

6

Grundmark et al.

2010

Sweden

Cohort

237

NA

Measurement

Database

NA

5

Martin et al.

2010

Norway

Cohort

1,974

50.3 (SD 15.2)

Physical examination

Cancer registry

Age, height, BMI, smoking, marital status, education, physical activity, diabetes and country of origin

8

Stocks et al.

2010

Sweden

Cohort

10,002

70.1 (SD 8.4)

Health examination

Cancer registry

Age, smoking and BMI

7

Beebe-Dimmer et al.

2009

US

Case-control

637

62

Medical records

Database

Age, PSA screening, diabetes, BMI, HDL and triglycerides

6

Inoue et al.

2009

Japan

Cohort

86

40–69

Measurement

Cancer registry

Age, study area, smoking, ethanol intake and serum cholesterol

7

Beebe-Dimmer et al.

2007

US

Case-control

139

40–79

Questionnaire

Cancer registry

Age and smoking history

7

Tuohimaa et al.

2007

Finland

Nested case-control

132

62.1 (SD 4.9)

Measurement

Cancer registry

Vitamin D

5

Lund Håheim et al.

2006

Norway

Cohort

507

40–49

Questionnaire

Cancer registry

Age

5

Tande et al.

2006

US

Cohort

385

45–64

Clinical examination

Cancer registry

Age, race, family history, education, smoking, ethanol intake, caloric intake and milk intake

6

Ronquist et al.

2004

UK

Nested case-control

1,013

50–79

Database

Medical record

Age, smoking, BMI, alcohol, diabetes, IHD, HF, prostatism and calendar year

6

Fitzpatrick et al.

2001

US

Cohort

209

≥65

Clinical examination

Medical record

Age, race and BMI

6

Rosengren et al.

1998

Sweden

Cohort

263

47–55

Screening examination

Cancer registry

Age

5

Friedman et al.

1997

US

Cohort

2,297

30–79

Health checkup

Cancer registry

Age, race, BMI and alcohol consumption

7

Tulinius et al.

1997

Iceland

Cohort

524

50.3 (SD 11)

Questionnaire

Cancer registry

Age

5

  1. PSA, prostate-specific antigen; NOS, Newcastle-Ottawa Scale; yr, year; SD, standard deviation; BMI, body mass index; IHD, ischemic heart disease; HF, heart failure; HDL, high density lipoprotein; NA, not available.