Table 1 Clinicopathological features of the included patients in cohort 1 (N = 378).

From: Pretreatment neutrophil-to-lymphocyte ratio and its dynamic changes are associated with the overall survival in advanced cancer patients undergoing palliative care

Clinicopathological features

N

NLR (continuous)

P

NLR (dichotomous)

P

Median (IQR)

LNLR (n = 89)

HNLR (n = 289)

Gender

  

0.029

  

0.130

 Male

209

5.813 (3.667~10.50)

 

43 (48.31%)

166 (57.44%)

 

 Female

169

5.333 (3.091~8.889)

 

46 (51.69%)

123 (42.56%)

 

Age

  

0.756

  

0.3070

 <65

203

5.667 (3.273~9.833)

 

52 (58.43%)

151 (52.25%)

 

 ≥65

175

5.500 (3.460~9.618)

 

37 (41.57%)

138 (47.75%)

 

Tumor stage

  

0.054

  

0.473

 III

23

3.833 (3.133~6.000)

 

4 (4.49%)

19 (6.57%)

 

 IV

355

5.667 (3.429~9.889)

 

85 (95.51%)

270 (93.43%)

 

Primary tumor site

  

0.295

  

0.551

 Gastrointestinal tumors

198

6.163 (3.696~10.50)

 

40 (44.94%)

158 (54.67%)

 

 Thoracic cancers

86

5.422 (3.273~9.091)

 

23 (25.84%)

63 (21.80%)

 

 Urogenital neoplasms

59

4.867 (3.050~7.571)

 

15 (16.85%)

44 (15.22%)

 

 Head and neck neoplasms

16

5.962 (2.640~9.778)

 

5 (5.62%)

11 (3.81%)

 

 Other tumors

19

4.417 (2.750~8.385)

 

6 (6.74%)

13 (4.50%)

 

Palliative care

  

<0.001

  

0.196

 PCR

99

4.364 (2.875~6.667)

 

28 (31.46%)

71 (24.57%)

 

 BSC

279

6.125 (3.583~10.73)

 

61 (68.54%)

218 (75.43%)

 

Family history

  

0.979

  

0.109

 No

264

5.333 (3.462~9.889)

 

58 (65.17%)

206 (71.28%)

 

 Yes

109

6.243 (3.111~9.200)

 

28 (31.46%)

81 (28.03%)

 

 Unknown

5

14.72 (10.44~19.00)

 

3 (3.37%)

2 (0.69%)

 

Smoking history

  

0.013

  

0.301

 No

265

5.250 (3.143~9.091)

 

68 (76.40%)

197 (68.17%)

 

 Yes

105

6.404 (3.778~10.63)

 

19 (21.35%)

86 (29.76%)

 

 Unknown

8

9.722 (7.517~11.63)

 

2 (2.25%)

6 (2.08%)

 

Concomitant disease

  

0.850

  

0.311

 No

229

5.558 (3.279~9.861)

 

58 (65.17%)

171 (59.17%)

 

 Yes

149

5.500 (3.533~9.429)

 

31 (34.83%)

118 (40.83%)

 

Nutrient status

  

0.004

  

0.204

 Normal

107

4.375 (2.800~7.333)

 

31 (34.83%)

76 (26.30%)

 

 Abnormal

268

6.021 (3.652~10.59)

 

57 (64.04%)

211 (73.01%)

 

 Unknown

3

3.778 (2.480~13.25)

 

1 (1.12%)

2 (0.69%)

 

Hospital Stay

  

0.335

  

0.250

 ≤14 days

205

5.764 (3.458~10.83)

 

53 (59.55%)

152 (52.60%)

 

 >14 days

173

5.444 (3.308~9.091)

 

36 (40.45%)

137 (47.40%)

 
  1. NLR: neutrophil-to-lymphocyte ratio; IQR: inter quartile ranges; LNLR: low NLR (pretreatment NLR ≤ 3); HNLR: high NLR (pretreatment NLR > 3); PCR: palliative chemoradiotherapy; BSC: best supportive care.
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