Table 2 Clinicopathological features of the included patients in cohort 2 (N = 106).

From: Pretreatment neutrophil-to-lymphocyte ratio and its dynamic changes are associated with the overall survival in advanced cancer patients undergoing palliative care

Clinicopathological features

N

NLR change (continuous)

P

NLR change (dichotomous)

P

Median (IQR)

Decreased (n = 43)

Increased (n = 63)

Gender

  

0.735

  

0.611

 Male

56

0.550 (−0.759~3.444)

 

24 (55.81%)

32 (50.79%)

 

 Female

50

0.572 (−1.209~2.500)

 

19 (44.19%)

31 (49.21%)

 

Age

  

0.661

  

0.325

 <65

63

0.550 (−1.180~3.518)

 

28 (65.12%)

35 (55.56%)

 

 ≥65

43

0.667 (−0.381~2.500)

 

15 (34.88%)

28 (44.44%)

 

Tumor stage

  

0.009

  

0.004

 III

13

−1.569 (−2.548~−0.250)

 

10 (23.26%)

3 (4.76%)

 

 IV

93

0.950 (−0.667~3.518)

 

33 (76.74%)

60 (95.24%)

 

Primary tumor site

  

0.147

  

0.609

 Gastrointestinal tumors

60

1.115 (−0.718~4.000)

 

24 (55.81%)

36 (57.14%)

 

 Thoracic cancers

14

0.343 (−0.883~7.980)

 

5 (11.63%)

9 (14.29%)

 

 Urogenital neoplasms

23

−0.250 (−2.548~1.250)

 

12 (27.91%)

11 (17.46%)

 

 Head and neck neoplasms

6

2.212 (1.110~3.444)

 

1 (2.33%)

5 (7.94%)

 

 Other tumors

3

0.550 (−1.254~4.650)

 

1 (2.33%)

2 (3.17%)

 

Palliative care

  

0.001

  

0.001

 PCR

54

−0.315 (−1.832~1.486)

 

30 (69.77%)

24 (38.10%)

 

 BSC

52

1.740 (0.233~4.166)

 

13 (30.23%)

39 (61.90)

 

Family history

  

0.467

  

0.148

 No

73

0.521 (−1.068~3.171)

 

33 (76.74%)

40 (63.49%)

 

 Yes

33

0.773 (−0.374~3.518)

 

10 (23.26%)

23 (36.51%)

 

Smoke history

  

0.812

  

0.994

 No

74

0.619 (−0.900~2.500)

 

30 (69.77%)

44 (69.84%)

 

 Yes

32

0.485 (−1.276~3.842)

 

13 (30.23%)

19 (30.16%)

 

Concomitant disease

  

0.825

  

0.531

 No

63

0.572 (−0.900~3.444)

 

24 (55.81%)

39 (61.90%)

 

 Yes

43

0.533 (−1.254~2.702)

 

19 (44.19%)

24 (38.10%)

 

Nutrient status

  

0.311

  

0.356

 Normal

42

0.419 (−1.254~2.375)

 

20 (46.51%)

22 (34.92%)

 

 Abnormal

63

0.619 (−0.759~3.900)

 

23 (53.49%)

40 (63.49%)

 

 Unknown

1

2.702 (2.702~2.702)

 

0 (0.00%)

1 (1.59%)

 

Hospital stay

  

0.051

  

0.323

 ≤14 days

53

0.233 (−1.209~2.375)

 

24 (55.81%)

29 (46.03%)

 

 >14 days

53

1.250 (−0.381~3.518)

 

19 (44.19%)

34 (53.97%)

 
  1. NLR: neutrophil-to-lymphocyte ratio; IQR: inter quartile ranges; PCR: palliative chemoradiotherapy; BSC: best supportive care.
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