Table 5 Unadjusted and adjusted HRs for overall survival stratified by NLR change in cohort 2 (N = 106).

From: Pretreatment neutrophil-to-lymphocyte ratio and its dynamic changes are associated with the overall survival in advanced cancer patients undergoing palliative care

Prognostic factors

 

Unadjusted HR (95% CI)

P

Adjusted HR* (95% CI)

P

NLR

Decreased

Reference

 

Reference

 
 

Increased

2.609 (1.638~4.154)

<0.001

2.506 (1.474~4.261)

0.001

NLR change

LNLR → LNLR

Reference

 

Reference

 
 

LNLR → HNLR

3.017 (1.306~6.973)

0.010

4.061 (1.632~10.10)

0.003

 

HNLR → LNLR

0.759 (0.344~1.678)

0.496

0.939 (0.401~2.201)

0.886

 

HNLR → HNLR

2.237 (1.208~4.141)

0.010

2.936 (1.530~5.634)

0.001

  1. NLR: neutrophil-to-lymphocyte ratio; HR, hazard ratio; CI, confidence interval.
  2. *Cox regression model controlling for Age; Gender; Tumor stage; Primary tumor site; Palliative care; Family history; Smoke history; Nutrient status; Concomitant disease; Hospital stay; Albumin level.
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