Table 2 Univariate and Multivariate Analysis for Survivals.
Prognostic Factors | Disease-specific Progression-free Survival | Overall Survival | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Univariate | Multivariate | Univariate | Multivariate | |||||||||
HR for PD | (95% CI) | P value | HR for PD | (95% CI) | P value | HR for death | (95% CI) | P value | HR for death | (95% CI) | P value | |
Age, (yr) | ||||||||||||
≥50 vs. <50 | 1.108 | (0.558–2.199) | 0.770 | 0.930 | (0.510–1.697) | 0.814 | ||||||
Surgery after CCRT | ||||||||||||
Yes vs. No | 0.142 | (0.049–0.413) | <0.001 | 0.160 | (0.052–0.486) | 0.001 | 0.189 | (0.079–0.455) | <0.001 | 0.19 | (0.076–0.472) | <0.001 |
ECOG PS | ||||||||||||
0–1 vs.≥ 2 | 0.604 | (0.286–1.272) | 0.185 | 0.296 | (0.157–0.556) | <0.001 | 0.276 | (0.138–0.553) | <0.001 | |||
TNM Stage (7th ed.) | <0.001 | <0.001 | 0.001 | 0.003 | ||||||||
Stage II | 0.072 | (0.009–0.591) | 0.014 | 0.041 | (0.004–0.388) | 0.005 | 0.077 | (0.010–0.612) | 0.015 | 0.112 | (0.013–0.944) | 0.044 |
Stage III | 0.210 | (0.094–0.470) | <0.001 | 0.186 | (0.077–0.452) | 0.000 | 0.310 | (0.154–0.626) | 0.001 | 0.306 | (0.147–0.636) | 0.002 |
Stage IV | reference | reference | reference | reference | ||||||||
CTC number (cells/mL) | ||||||||||||
≥21.0 vs. <21.0 | 2.022 | (1.010–4.049) | 0.047 | 3.113 | (1.427–6.791) | 0.004 | 2.661 | (1.375–5.150) | 0.024 | |||
CTC number (cells/mL) | 1.002 | (0.999–1.004) | 0.139 | 1.003 | (1.001–1.005) | 0.002 | 1.002 | (1.000–1.004) | 0.028 | |||
