Table 2 Analysis of germline transmission efficiency in founders derived from piggyBac mediated hSIRPa BAC transposition.

From: Comparative Analysis of piggyBac, CRISPR/Cas9 and TALEN Mediated BAC Transgenesis in the Zygote for the Generation of Humanized SIRPA Rats

hSIRPa-BAC-TIRs Founders

Number of pups

Number of PCR positive pups

1.6

20

13

4.2 (fragmented BAC)

25

5

5.4

22

0

5.5 (random BAC insertion)

22

0

5.7

27

2

8.1

NA

NA

9.2

7

0

9.4

20

8

  1. Refers to founders that died before mating.