Figure 6: Relationship among variant, allele frequency, and structure.
From: The structural origin of metabolic quantitative diversity
(a) Scatter plot of the concentration distribution of plasma phenylalanine. Heterozygotes of rs118092776, rs79931499, and rs746203167 are colored orange, red, and pink, respectively. Others are colored grey. (b) Mapping of the three non-synonymous variants on the structure of rat PAH. Three residues corresponding to the position of each non-synonymous variant are shown by a sphere model. (d) Schematic view of the relationship among variant, allele frequency, and structure. We propose a new category for variant, omic, whose variants partially influence omics environments of individuals.
