Figure 1: Differential miRNA expression profiles in db/db mice.
From: Cross talk between miR-214 and PTEN attenuates glomerular hypertrophy under diabetic conditions
(A) The blood glucose level in mice. (B) UAE in mice. (C) PAS staining in glomeruli from mice (original magnification ×400). Scale bars: 20 μm. (D) Heat map for differential miRNA profiles in renal cortex between db/db and db/m groups. (E) Representative images for the isolated glomeruli (Original magnification ×100).Scale bars: 20 μm. (F) Quantitative real-time PCR in isolated glomeruli to validate the miRNA data and confirm the gene expression results obtained from microarray analysis. All data were expressed as means ± SD (n = 10/each group). ▲p < 0.05, ▲▲p < 0.01.
