Figure 1: The differential expression levels of urine miRNAs in patients with ICP versus healthy pregnancies. | Scientific Reports

Figure 1: The differential expression levels of urine miRNAs in patients with ICP versus healthy pregnancies.

From: Feasibility of urinary microRNA profiling detection in intrahepatic cholestasis of pregnancy and its potential as a non-invasive biomarker

Figure 1

The expression of candidate miRNAs was confirmed by individual qRT-PCR in an independent cohort of 90 (50 control vs 40 ICP) urine samples. The expression levels of hsa-miR-369-5p, hsa-miR-16, hsa-miR-671-3p, hsa-miR-151-3p, has-miR-489 and hsa-miR-300 were significantly different between ICP and control groups (p < 0.05and FDR < 0.05). The values are normalized by geometric mean normalization of cel-miR-1832 and cel-miR-5594-5p, shown as relative expression at y-axis. The upper and lower limits of the boxes and the lines inside the boxes indicate the 75th and 25th percentiles and the median, respectively. Upper and lower horizontal bars denote the 90th and 10th percentiles.

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