Table 1 Main clinical characteristics of the study groups.
Variables | Screening set | P value | Validation set | P value | ||
|---|---|---|---|---|---|---|
Controls (n = 10) | ICP (n = 10) | Controls (n = 50) | ICP (n = 40) | |||
Maternal age, y | 28.80 ± 2.53 | 29.30 ± 5.56 | 0.060 | 28.93 ± 3.40 | 28.89 ± 4.10 | 0.940 |
Gestational week | 31.80 ± 1.75 | 32.00 ± 3.02 | 0.080 | 32.36 ± 2.51 | 34.00 ± 2.15 | 0.110 |
TBA, μmol/L | 2.76 ± 0.73 | 22.32 ± 14.66 | 0.004 | 2.67 ± 1.36 | 26.77 ± 21.11 | 0.000 |
TBIL, μmol/L | 7.73 ± 3.17 | 12.69 ± 6.50 | 0.117 | 7.60 ± 2.64 | 10.46 ± 5.63 | 0.004 |
DBIL, μmol/L | 1.79 ± 1.28 | 3.43 ± 2.11 | 0.122 | 1.74 ± 0.95 | 5.28 ± 5.03 | 0.000 |
ALT, IU/L | 13.20 ± 4.37 | 54.73 ± 67.82 | 0.006 | 15.98 ± 17.72 | 88.70 ± 99.79 | 0.000 |
AST, IU/L | 16.80 ± 2.66 | 41.40 ± 45.29 | 0.003 | 18.76 ± 9.69 | 53.18 ± 49.27 | 0.000 |
ALP, IU/L | 96.00 ± 26.42 | 154.70 ± 112.46 | 0.004 | 98.18 ± 29.20 | 168.98 ± 100.01 | 0.000 |
GGT, IU/L | 13.20 ± 10.68 | 31.60 ± 35.04 | 0.137 | 14.61 ± 7.93 | 30.11 ± 26.34 | 0.000 |
