Table 6 The allele frequency comparison between the meta-analysis and 1000 Genomes Project.

From: Comprehensive Assessment of the Association between FCGRs polymorphisms and the risk of systemic lupus erythematosus: Evidence from a Meta-Analysis

Polymorphism

Populations

Meta-analysis(alleles frequencies)

 

Cases

Controls

1000 Genomes(Alleles frequencies)

A

G

A

G

A

G

SNP rs1801274

Caucasian

0.445

0.555

0.474

0.526

0.500(EUR)

0.5(EUR)

Asian

0.652

0.348

0.697

0.303

0.722(ASN)

0.278(ASN)

African

0.568

0.432

0.602

0.398

0.512(AFR)

0.488(AFR)

African Americans

0.393

0.607

0.529

0.471

0.525(ASW)

0.475(ASW)

Mixed population

0.479

0.521

0.448

0.552

  

Non-Caucasian

0.493

0.507

0.436

0.564

  

All

0.563

0.437

0.595

0.405

0.57(ALL)

0.43(ALL)

SNP rs1050501

 

C

T

C

T

C

T

Asian

0.280

0.720

0.248

0.752

0.255(ASN)

0.745(ASN)

Caucasian

0.128

0.872

0.107

0.893

0.123(EUR)

0.877(EUR)

African

0.572

0.428

0.433

0.567

0.248(AFR)

0.752(AFR)

African-American

0.241

0.759

0.292

0.708

0.213(ASW)

0.787(ASW)

All

0.249

0.751

0.198

0.802

0.188(ALL)

0.812(ALL)

SNP rs396991

 

T

G

T

G

T

G

Caucasian

0.659

0.341

0.629

0.371

0.731(EUR)

0.269(EUR)

Asian

0.673

0.327

0.657

0.343

0.731(ASN)

0.269(ASN)

African-American

0.664

0.336

0.659

0.341

0.713(ASW)

0.287(ASW)

Mixed population

0.622

0.378

0.557

0.443

  

Non-Caucasian

0.600

0.400

0.624

0.376

  

African

0.586

0.414

0.542

0.458

0.785(AFR)

0.215(AFR)

All

0.663

0.337

0.641

0.359

0.755(ALL)

0.245(ALL)

  1. EUR European ancestry, ASN Asian ancestry, AFR African ancestry, ASW Americans of African Ancestry, ALL All individuals from phase 1 of the 1000 Genomes Project.
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