Figure 3
From: Up- regulation of miR-328-3p sensitizes non-small cell lung cancer to radiotherapy
miR-328-3p over-expression increased radio sensitivity and promoted DNA damage of A549 cells.
(A,B) Comet assay was performed to evaluate DNA damage response following miR-328-3p transfection. ANOVA test was used to determine the statistical significance of differences among the groups. Results presented as mean ± SEM of values obtained in three independent experiments. (C,D) Blue represents stained nuclei and green represents stained γ-H2AX foci. Mean number of foci per cell for various doses shown after 0 to 8 Gy of irradiation. *p < 0.05, compared to the parental control.
