Figure 5
4D MIOCT reveals previously unidentified volumetric tissue deformation during human retinal brushing.
4D MIOCT was performed during retinal brushing to initiate peeling of a pathologic membrane in human retinal surgery. (A) Excerpts from a 4D MIOCT recording showing retinal brushing with a diamond dusted membrane scraper (DDMS) (purple) around a macular hole (MH) (blue) (Movie S1). The corresponding frames from the surgical camera used to record the view through the operating microscope are shown above the MIOCT data. The macular hole is more readily identifiable in the MIOCT volumes. In addition, volumetric retinal deformation during the brushing maneuver and residual retinal deformation (RRD) (red) after the maneuver was only visible in the MIOCT data. (B) Excerpts from a 4D MIOCT illustrating retinal brushing with a microsurgical flex loop (FL) (yellow) and elevated blood vessels (BV) (black) (Movie S2). Compared to (A), the flex loop is less abrasive and results in less overall retinal deformation and no residual deformation. The volumetric frames rates for (A,B) were 3.33 and 5.0 volumes/second, respectively. Time stamps are in seconds (yellow numbers). The green dashed box denotes the lateral MIOCT field of view. The volumetric MIOCT field of view was 3 × 5 × 5 mm.
