Figure 6
4D MIOCT enhanced visualization during removal of human pathologic translucent membranes.
4D MIOCT was performed during peeling of epiretinal membranes (ERM) in human retinal surgery. (A) Excerpts of a 4D MIOCT recording illustrating grasping and peeling of an ERM (red) with surgical intraocular forceps (IF) (purple) (Movie S3). The maneuver is visualized in the surgical camera frames (top row) and volumes (bottom row). The ERM flap used to initiate the peeling is more readily identifiable in the MIOCT data. Additionally, the angle and membrane tension during the ERM peel are more appreciable in the MIOCT images. (B–E) show the camera frame (B), B-scan (C) and volumetric renderings (D,E) of ERM (red) around a macular hole (MH) (blue) before peeling in a separate surgery. The exact axial proximity of the ERM to underlying healthy retina is only directly visible in the B-scan (C) and volumes (D,E). The complex 3D ERM microarchitecture could be inspected in volumetric MIOCT data from different perspectives (D,E). (F–I) shows similar views of the macula after ERM peeling. The volumetric frame rate was 3.33 volumes/second. Time stamps are in seconds (yellow). The green dashed box denotes the lateral MIOCT field of view. The volumetric MIOCT field of view was 3 × 5 × 5 mm.
