Figure 7
4D MIOCT-guided identification and resolution of abnormal adhesion of iris to the graft/cornea interface during a human corneal transplantation.
4D MIOCT guidance was necessary to treat the lesion the lesion since it could not be visualized top-down through the operating microscope. (A–C) show the microscope view (A), B-scan (B) and volume (C) at the time during which the surgeon identified the abnormal iris adhesion (IA) to cornea/graft interface (red) in the MIOCT data. The white rectangle in the volume denotes the location of the B-scan. (D) Excerpts of 4D MIOCT recording during treatment of the lesion (Movie S4). Using 4D MIOCT for localization guidance, the surgeon was able to direct a cannula (CA) (blue) and inject viscoelastic between the iris and corneal graft to release the adhesion. Further evaluation using MIOCT revealed resolution of the adhered iris with clear intervening space between iris and cornea. The volumetric rate for (D) was 0.5 volumes/second. Time stamps (yellow) are in seconds. The green dashed box denotes the lateral MIOCT field of view. The volumetric MIOCT field of view was 6 × 10 × 10 mm.
