Figure 8
4D MIOCT-guided unfolding of graft below native cornea during human partial thickness corneal transplantation.
4D MIOCT imaging was necessary to determine the axial distance between the graft and native cornea, which was invisible through the operating microscope. (A) Frames from the surgical camera (top) and excerpts from a 4D MIOCT recording shown in B-scans (middle) and volumes (bottom) during graft insertion and unfolding (Movie S5). As the graft (GR) (blue) unfolded, the surgeon used 4D MIOCT data to monitor the graft/cornea interface (GCI) (orange) and to ensure graft/cornea apposition. The volumetric rate for was 0.5 volumes/second. An image artifact due to specular reflection (SR) (yellow) from the corneal apex is present in the middle of the volumes. Time stamps (black) are in seconds. The white rectangle in the volumes denotes the location of the B-scan. The green dashed box denotes the lateral MIOCT field of view. The volumetric MIOCT field of view was 6 × 10 × 10 mm.
