Figure 10: Changes in metabolic functions of wild type and snrk1α1/α2 during the time course measurement in extended night.

The metabolic functions for wild type (a) and snrk1α1/α2 (b) were derived by the inverse calculation of the biochemical Jacobian according to Nägele et al.92. Individual entries of the Jacobian represent changes in reaction rates in response to metabolite concentration changes. Individual Jacobian entries were summed up into metabolic functions and plotted over the time course. A significant difference is the missing early response in the snrk1α1/α2 mutant in the beginning of the extended night phase. A detailed overview of characteristic components of the metabolic functions and their related biochemical pathways is provided in the Supplementary Table S5.