Table 1 Demographics and clinical characteristics of children with MHHs.

From: Clinical features and management of multifocal hepatic hemangiomas in children: a retrospective study

Variables

≤4 Cutaneous IHs

≥5 Cutaneous IHs

Total

P-values

n = 15

n = 27

n = 42

Age at diagnosis (month)*,

2.0 (1.5–3.0)

2.1 (1.5–3.0)

2.1 (1.5–3.0)

0.65

Gender

   

1.00

 Male

4 (26.7)

7 (25.9)

11 (26.2)

 

 Female

11 (73.3)

20 (74.1)

31 (73.8)

 

Gestational age

   

0.49

 Term born

3 (20.0)

9 (33.3)

12 (28.6)

 

 Born prematurely

12 (80.0)

18 (66.7)

30 (71.4)

 

Hepatomegaly

   

0.72

 Yes

3 (20.0)

8 (29.6)

11 (26.2)

 

 No

12 (80.0)

19 (70.4)

31 (73.8)

 

Congestive heart failure

   

1.00

 Yes

1 (6.7)

2 (7.4)

3 (7.1)

 

 No

14 (93.3)

25 (92.6)

39 (92.9)

 

Hypothyroidism

   

0.86

 Yes

0 (0)

2 (7.4)

2 (4.8)

 

 No

12 (80.0)

19 (70.4)

31 (73.8)

 

 Unknown

3 (20.0)

6 (22.2)

9 (21.4)

 

Number of MHH lesions

   

0.43

 2–4

8 (53.3)

9 (33.3)

17 (40.5)

 

 5–9

4 (26.7)

8 (29.6)

12 (28.6)

 

 ≥10

3 (20.0)

10 (37.0)

13 (30.9)

 

Liver arteriovenous shunt

   

0.69

 Yes

2 (13.3)

6 (22.2)

8 (19.0)

 

 No

13 (86.7)

21 (77.8)

34 (81.0)

 

Treatment for MHH

   

0.09

 Yes

3 (20.0)

11 (40.7)

14 (33.3)

 

 No

12 (80.0)

16 (59.3)

28 (66.7)

 

Mortality

   

0.53

 Yes

0 (0)

2 (7.4)

2 (4.8)

 

 No

15 (100)

25 (92.6)

40 (95.2)

 

Duration of follow-up (month)

44.0 (30.0–70.0)

48.0 (36–72.0)

48.0 (36.0–70.1)

0.50

  1. *Age at diagnosis was defined as the date multifocal hepatic hemangiomas were first confirmed by imaging.
  2. Values are presented as a median (interquartile range).
  3. Values are presented as a number (percentage).
  4. MMH: multifocal hepatic hemangioma; IH: infantile hemangioma.