Figure 1 | Scientific Reports

Figure 1

From: Filtrating colorectal cancer associated genes by integrated analyses of global DNA methylation and hydroxymethylation in cancer and normal tissue

Figure 1

Boxplot showing distribution of methylation and hydroxymethylation levels of each detectable CCGG sites in genome wide of CRCs (red) and matched normal sample (bule).

The hydroxymethylation level is defined as the ratio between ‘C + mC + hmC’ and ‘C + mC’ tags, while methylation abundance is defined as the ratio between tag counts of “C + mC” and “C” libraries. T1 is a sign of patient 1’s tumor sample, while N1 is a sign of patient 1’s normal sample.

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