Figure 1: Liver injury and weight loss are increased in animals with combined steatosis and cholestasis compared to cholestasis alone.

(A) Plasma levels of alanine transaminase (ALT), alkaline phosphatase (ALP), and gamma-glutamyl transferase (GGT). (B) Animal weight change during the third week of the experiment, starting directly before sham surgery or BDL. Data represent means ± SD of n = 5–6/group; 1, p < 0.05 versus sham; 2, p < 0.05 versus MCD; 3, p < 0.05 versus BDL.