Figure 7: Serum IgG titers against M2e induced by RHDV-M2 VLPs correlate with protection against influenza A virus challenge. | Scientific Reports

Figure 7: Serum IgG titers against M2e induced by RHDV-M2 VLPs correlate with protection against influenza A virus challenge.

From: Rabbit hemorrhagic disease virus capsid, a versatile platform for foreign B-cell epitope display inducing protective humoral immune responses

Figure 7

Sera samples obtained from the indicated groups of mice, just before the lethal challenge, were tested by ELISA for antibodies against M2e. Values represent the antibody titter of each individual mouse. The GMT was calculated for each group (solid lines). The dashed line depicts the antibody titer value of 39,000. All mice that elicited anti-M2e IgG titers above this threshold value survived the influenza virus lethal challenge.

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